858362-09-1Relevant articles and documents
Trifluoromethyl arylamides with antileukemia effect and intracellular inhibitory activity over serine/arginine-rich protein kinases (SRPKs)
Siqueira, Raoni Pais,Barros, Marcus Vinícius de Andrade,Barbosa, éverton de Almeida Alves,Onofre, Thiago Souza,Gon?alves, Victor Hugo Sousa,Pereira, Higor Sette,Silva Júnior, Abelardo,de Oliveira, Leandro Licursi,Almeida, Márcia Rogéria,Fietto, Juliana Lopes Rangel,Teixeira, Róbson Ricardo,Bressan, Gustavo Costa
, p. 97 - 109 (2017)
The serine/arginine-rich protein kinases (SRPKs) have frequently been found with altered activity in a number of cancers, suggesting they could serve as potential therapeutic targets in oncology. Here we describe the synthesis of a series of twenty-two tr
METHOD OF REGULATING PHOSPHORYLATION OF SR PROTEIN AND ANTIVIRAL AGENTS COMPRISING SR PROTEIN ACTIVITY REGULATOR AS THE ACTIVE INGREDIENT
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Page/Page column 36, (2008/06/13)
The present invention provides: (1) antiviral agents that act by reducing or inhibiting the activity of SR proteins, more specifically, (i) antiviral agents that act by enhancing dephosphorylation of SR proteins, and (ii) antiviral agents that act by inhi