85840-34-2Relevant academic research and scientific papers
On the Amination of 3-Nitro-1,8-naphthyridines (1,2)
Wozniak, Marian,Plas, Henk C. van der,Veldhuizen, Beb van
, p. 9 - 11 (2007/10/02)
A number of 3-nitro-2-X-1,8-naphthyridines (X = H, Cl, NH2, OEt) were successfully aminated into the corresponding 4-amino-3-nitro-2-X-naphthyridines, using liquid ammonia and potassium permanganate as reagents. 4-Amino-1,4-dihydro-3-nitro-2-X-1,8-naphthyridines are the actual species being oxidized by the potassium permanganate; their existence has been proved by 1H nmr spectroscopy.
