85862-60-8Relevant articles and documents
Green synthesis of 1-monosubstituted 1,2,3-triazoles via 'click chemistry' in water
Wu, Luyong,Yan, Bo,Yang, Guo,Chen, Yuxue
, p. 397 - 400 (2013)
The copper-catalyzed click reaction of organic azides with acetylene gas to give 1,2,3-triazoles using water as solvent was studied. The best yields are obtained in the presence of 10 mol% of CuI and 20 mol% of Et3N. Several 1-substituted triaz
COMPOUNDS
-
Page/Page column 36-37; 71; 72, (2020/03/23)
A compound for use in the treatment of a disease ameliorated by the inhibition of Notum of formula (I): (I)
One-pot synthesis of 1-monosubstituted-1, 2, 3-triazoles from 2-methyl-3-butyn-2-ol
Liu, Yaowen,Han, Chunmei,Ma, Xinyuan,Yang, Jianhua,Feng, Xuepu,Jiang, Yubo
supporting information, p. 650 - 653 (2018/01/15)
An efficient method for the synthesis of 1-monosubstituted-1, 2, 3-triazoles from 2-methyl-3-butyn-2-ol under copper catalyst conditions has been developed through a one-step one-pot sequence. This method provides a concise and efficient pathway to synthesize 1-monosubstituted-1, 2, 3-triazole derivatives in good to excellent yields.