858675-47-5Relevant academic research and scientific papers
Design and synthesis of iminosugar-based inhibitors of glucosylceramide synthase: The search for new therapeutic agents against Gaucher disease
Boucheron, Charlotte,Desvergnes, Valerie,Compain, Philippe,Martin, Olivier R.,Lavi, Alan,Mackeen, Muckram,Wormald, Mark,Dwek, Raymond,Butters, Terry D.
, p. 1747 - 1756 (2007/10/03)
A series of iminosugars bearing two or three alkyl chains ('iminoglycolipids') were designed as ceramide mimics and analogues of N-butyl 1-deoxynojirimycin (N-Bu DNJ, Zavesca). This orally active iminosugar inhibits the biosynthesis of glucosyl
