858676-47-8

Basic information

• Product Name: (+)-methyl (2S,3S,4S,6R)-[6-(2-benzyloxyethyl)-3-methyl-(4-triisopropylsilanyloxy)-tetrahydropyran-2-yl]-acetate
• Synonyms: (+)-methyl (2S,3S,4S,6R)-[6-(2-benzyloxyethyl)-3-methyl-(4-triisopropylsilanyloxy)-tetrahydropyran-2-yl]-acetate
• CAS NO: 858676-47-8
• Molecular Weight: 478.745
• Mol File: 858676-47-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (+)-methyl (2S,3S,4S,6R)-[6-(2-benzyloxyethyl)-3-methyl-(4-triisopropylsilanyloxy)-tetrahydropyran-2-yl]-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-methyl (2S,3S,4S,6R)-[6-(2-benzyloxyethyl)-3-methyl-(4-triisopropylsilanyloxy)-tetrahydropyran-2-yl]-acetate(858676-47-8)
• EPA Substance Registry System: (+)-methyl (2S,3S,4S,6R)-[6-(2-benzyloxyethyl)-3-methyl-(4-triisopropylsilanyloxy)-tetrahydropyran-2-yl]-acetate(858676-47-8)

Safety Data

• Hazardous Substances Data: 858676-47-8(Hazardous Substances Data)

Upstream product

• 858676-46-7 [(2S,3R,4S,6R)-6-(2-Benzyloxy-ethyl)-4-hydroxy-3-methyl-tetrahydro-pyran-2-yl]-acetic acid 
• 870095-89-9 (+)-methyl (2E,5S,7E)-5-(2-benzyloxyethyl)-4-oxa-nona-2,7-dienoate 
• 858676-45-6 (+)-methyl (2S,3S,4S,6R)-[6-(2-benzyloxyethyl)-4-hydroxy-3-methyltetrahydropyran-2-yl]-acetate 
• 13154-24-0 triisopropylsilyl chloride 
• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 

Relevant articles and documents

Total synthesis of a diastereomer of the marine natural product clavosolide A

The first total synthesis of the reported structure of the sponge metabolite clavosolide A is described using a Prins cyclisation to assemble the tetrahydropyran core followed by manipulation of the side-chain, dimerisation and finally glycosidation. The Royal Society of Chemistry 2005.