85872-58-8Relevant academic research and scientific papers
Exploration of polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2- dihydroquinoline (PS-IIDQ) as new coupling agent for the synthesis of 8-substituted xanthine derivatives
Bandyopadhyay, Prabal,Sathe, Manisha,Sharma, Pratibha,Kaushik
, p. 4631 - 4635 (2012/09/05)
Polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline (PS-IIDQ), a polymer supported covalent coupling reagent, was successfully employed for the first time in the synthesis of 8-substituted xanthine derivatives. PS-IIDQ was observed
New 8-substituted xanthiene derivatives as potent bronchodilators
Berk, Barkin,Akguen, Huelya,Erol, Kevser,Sirmaguel, Basar,Gao, Zhan-Guo,Jacobson, Kenneth A.
, p. 974 - 980 (2008/09/18)
The synthesis and structure determination of 8-aryl/alkyl aryl 1, 3-dimethyl-3, 7-dihydropurin-2, 6-dione derivatives (1-13), was carried out in this study. Bronchodilator activity is investigated using isolated guinea-pig tracheal strips, pre-contracted
1,3-Dialkyl-8-(p-sulfophenyl)xanthines: Potent Water-Soluble Antagonistst for A1- and A2-Adenosine Receptors
Daly, J.W.,Padgett, W.,Shamim, M.T.,Butts-Lamb, P.,Waters, J.
, p. 487 - 492 (2007/10/02)
A series of 8-(substituted phenyl) derivatives of Theophylline and other 1,3-dialkylxanthines were evaluated for potency and selectivity as antagonists at A1- and A2-adenosine receptors in brain tissue.Theophylline has a similar pote
