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Z-4-chloro-6-(1',2'-dideoxy-5'-hydroxy-3',4'-O-isopropylidene-6'-O-trityl-D-ribo-hex-1'-enyl)-2-methylpyrimidine is a complex organic compound with a molecular structure that features a pyrimidine ring system. Z-4-chloro-6-(1',2'-dideoxy-5'-hydroxy-3',4'-O-isopropylidene-6'-O-trityl-D-ribo-hex-1'-enyl)-2-methylpyrimidine is characterized by the presence of a chloro group at the 4-position and a methyl group at the 2-position of the pyrimidine ring. The 6-position is substituted with a unique sugar-like moiety, which includes a 1',2'-dideoxy-5'-hydroxy-3',4'-O-isopropylidene-6'-O-trityl-D-ribo-hex-1'-enyl group. This group is a modified ribose sugar with a double bond at the 1' position, a hydroxyl group at the 5' position, and protective groups, the isopropylidene at the 3' and 4' positions, and a trityl group at the 6' position. The compound's structure suggests it may have potential applications in medicinal chemistry, particularly in the development of antiviral or anticancer drugs, due to its complex and specific functional groups.

85878-91-7

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85878-91-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 85878-91-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,8,7 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 85878-91:
(7*8)+(6*5)+(5*8)+(4*7)+(3*8)+(2*9)+(1*1)=197
197 % 10 = 7
So 85878-91-7 is a valid CAS Registry Number.

85878-91-7Relevant academic research and scientific papers

Synthesis of Homo-C-nucleosides using Pyrimidinylmethylenephosphoranes

Katagiri, Nobuya,Takashima, Kenichi,Kato, Tetsuzo,Sato, Sadao,Tamura, Chihiro

, p. 201 - 209 (2007/10/02)

The direct synthesis of homo-C-nucleosides from pyrimidinylmethylenephosphoranes and protected D-ribose is described.Reaction of 2,3-O-isopropylidene-5-O-trityl-D-ribose (9) with pyrimidinylmethylenephosphoranes (5)-(8) gave protected α-and β-homo-C-nucleosides (14)-(21) and pyrimidinylolefins (10)-(13) in good yields.The ratio of α- and β-nucleosides depended on the properties of phosphoranes.Treatment of compounds (10)-(13) with base such as triethylamine or 1,8-diazabicycloundec-7-ene (DBU) gave ring-closed products (14)-(21) in quantitative yields.Deprotection of compounds (14)-(21) with hydrochloric acid in either dioxane-water or methanol gave homo-C-nucleosides (22)-(32).

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