85879-02-3 Usage
Molecular structure
2,5-anhydro-1-chloro-1-deoxy-1-(6-oxo-3,6-dihydropyrimidin-4-yl)hexitol consists of a 6-membered heterocyclic ring with a chlorine and a deoxyhexose moiety.
Role in synthesis
It is a key intermediate in the synthesis of various pharmaceutical compounds.
Therapeutic potential
2,5-anhydro-1-chloro-1-deoxy-1-(6-oxo-3,6-dihydropyrimidin-4-yl)hexitol is a potent anti-tumor agent and also exhibits antiviral, anti-inflammatory, and antibacterial properties.
Research and development interest
It is of great interest to researchers and pharmaceutical companies due to its potential therapeutic applications.
Use as a building block
It is commonly used as a building block in the synthesis of novel drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 85879-02-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,8,7 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 85879-02:
(7*8)+(6*5)+(5*8)+(4*7)+(3*9)+(2*0)+(1*2)=183
183 % 10 = 3
So 85879-02-3 is a valid CAS Registry Number.
85879-02-3Relevant academic research and scientific papers
Synthesis of Homo-C-nucleosides using Pyrimidinylmethylenephosphoranes
Katagiri, Nobuya,Takashima, Kenichi,Kato, Tetsuzo,Sato, Sadao,Tamura, Chihiro
, p. 201 - 209 (2007/10/02)
The direct synthesis of homo-C-nucleosides from pyrimidinylmethylenephosphoranes and protected D-ribose is described.Reaction of 2,3-O-isopropylidene-5-O-trityl-D-ribose (9) with pyrimidinylmethylenephosphoranes (5)-(8) gave protected α-and β-homo-C-nucleosides (14)-(21) and pyrimidinylolefins (10)-(13) in good yields.The ratio of α- and β-nucleosides depended on the properties of phosphoranes.Treatment of compounds (10)-(13) with base such as triethylamine or 1,8-diazabicycloundec-7-ene (DBU) gave ring-closed products (14)-(21) in quantitative yields.Deprotection of compounds (14)-(21) with hydrochloric acid in either dioxane-water or methanol gave homo-C-nucleosides (22)-(32).
