858796-10-8

Upstream product

• 113616-57-2 5-Acetoxy-2,6-dibromo-hexanoic acid methyl ester 
• 104-80-3 tetrahydrofuran-2,5-dimethanol 

Relevant academic research and scientific papers

CONVERSION OF 1,2,5,6-HEXANETETROL (HTO) TO TETRAHYDROFURAN DICARBOXYLIC ACID (THFDCA)

Disclosed herein are methods for synthesizing useful intermediates and/or products from 1,2,5,6-hexanetetrol (HTO), which itself can be derived from a sugar. In an aspect, a process is provided for production of THFDCA from 1,2,5,6-hexanetetrol (HTO). The process comprises the steps of (a) ring closing to form a ring compound and (b) oxidizing using a catalyst comprising platinum and bismuth to form an acid mixture. Step (a) may be performed before or after step (b).

Preparation of Tetrahydrofurfuryl Alcohol Derivatives with Electron-Withdrawing Substituents from 4-Acetoxy-1,5-dibromopentane Derivatives

When 4-acetoxy-1,5-dibromopentane derivatives having the electron-withdrawing groups at the 1-position, which were obtained by Cu(I)-catalyzed photochemical addition of 2-acetoxy-1,3-dibromopropane to electron-deficient olefins, were subjected to treatment with silver nitrate, tetrahydrofurfuryl alcohol derivatives with the electron-withdrawing groups at the 5-position were obtained.