85892-05-3Relevant academic research and scientific papers
Diastereoselective α Allylation of Secondary and Tertiary Thioamides via Thio-Claisen Rearrangement. A Structural Proof of Z Secondary Thioamide Dianions and Z Tertiary Thioamide Anions
Tamaru, Y.,Furukawa, Y.,Mizutani, M.,Kitao, O.,Yoshida, Z.
, p. 3631 - 3639 (2007/10/02)
Highly diastereoselective α allylation of secondary and tertiary thioamides is achieved by making use of thio-Claisen rearrangement.From the correlation between the diastereoselectivities in products and the structures of allylating agents, the Z structures of secondary thioamide dianion (ca. 100percent Z) and tertiary thioamide anion (>97percent Z) are concluded.
STEREOSELECTIVE GENERATION OF Z-KETENE S,N-ACETAL FROM S-ALKYL ONIUM SALT OF THIOAMIDE AND ITS APPLICATION TO DIASTEREOSELECTIVE α-ALLYLATION OF THIOAMIDE
Tamaru, Y.,Mizutani, M.,Furukawa, Y.,Kitao, O.,Yoshida, Z.
, p. 5319 - 5322 (2007/10/02)
Highly diastereoselective α-allylation of thioamides has been achieved via S-allylation of thioamide, dehydrohalogenation, and thio-Claisen rearrangement sequences in one pot.
