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858945-23-0

C22H23N3O2 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 858945-23-0 Structure

  • Basic information

    1. Product Name: C22H23N3O2
    2. Synonyms:
    3. CAS NO:858945-23-0
    4. Molecular Formula:
    5. Molecular Weight: 361.444
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 858945-23-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C22H23N3O2(CAS DataBase Reference)
    10. NIST Chemistry Reference: C22H23N3O2(858945-23-0)
    11. EPA Substance Registry System: C22H23N3O2(858945-23-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 858945-23-0(Hazardous Substances Data)

858945-23-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 858945-23-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,8,9,4 and 5 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 858945-23:
(8*8)+(7*5)+(6*8)+(5*9)+(4*4)+(3*5)+(2*2)+(1*3)=230
230 % 10 = 0
So 858945-23-0 is a valid CAS Registry Number.

858945-23-0Upstream product

858945-23-0Downstream Products

858945-23-0Relevant articles and documents

Benzimidazole and imidazole inhibitors of histone deacetylases: Synthesis and biological activity

Bressi, Jerome C.,Jong, Ron de,Wu, Yiqin,Jennings, Andy J.,Brown, Jason W.,O'Connell, Shawn,Tari, Leslie W.,Skene, Robert J.,Vu, Phong,Navre, Marc,Cao, Xiaodong,Gangloff, Anthony R.

, p. 3138 - 3141 (2010)

A series of N-hydroxy-3-[3-(1-substituted-1H-benzoimidazol-2-yl)-phenyl]-acrylamides (5a-5ab) and N-hydroxy-3-[3-(1,4,5-trisubstituted-1H-imidazol-2-yl)-phenyl]-acrylamides (12a-s) were designed, synthesized, and found to be nanomolar inhibitors of human histone deacetylases. Multiple compounds bearing an N1-piperidine demonstrate EC50s of 20-100 nM in human A549, HL60, and PC3 cells, in vitro and in vivo hyperacetylation of histones H3 and H4, and induction of p21waf. Compound 5x displays efficacy in human tumor xenograft models.

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