859147-53-8

Basic information

• Product Name: N-1-[(1S,4R)-4-{(monomethoxytrityl)oxymethyl}cyclopentyl]-5'-O-(tert-butyldimethylsilyl)-2',3'-O-isopropylideneadenosine
• Synonyms: N-1-[(1S,4R)-4-{(monomethoxytrityl)oxymethyl}cyclopentyl]-5'-O-(tert-butyldimethylsilyl)-2',3'-O-isopropylideneadenosine
• CAS NO: 859147-53-8
• Molecular Weight: 792.063
• Mol File: 859147-53-8.mol

Chemical Properties

• CAS DataBase Reference: N-1-[(1S,4R)-4-{(monomethoxytrityl)oxymethyl}cyclopentyl]-5'-O-(tert-butyldimethylsilyl)-2',3'-O-isopropylideneadenosine(CAS DataBase Reference)
• NIST Chemistry Reference: N-1-[(1S,4R)-4-{(monomethoxytrityl)oxymethyl}cyclopentyl]-5'-O-(tert-butyldimethylsilyl)-2',3'-O-isopropylideneadenosine(859147-53-8)
• EPA Substance Registry System: N-1-[(1S,4R)-4-{(monomethoxytrityl)oxymethyl}cyclopentyl]-5'-O-(tert-butyldimethylsilyl)-2',3'-O-isopropylideneadenosine(859147-53-8)

Safety Data

• Hazardous Substances Data: 859147-53-8(Hazardous Substances Data)

Upstream product

• 664341-72-4 (1S,4R)-1-tert-butoxycarbonylamino-4-hydroxymethylcyclopentane 
• 204913-00-8 (1R,4S)-tert-butyl 3-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylate 
• 134003-03-5 (+)-2-Azabicyclo<2.2.1>heptan-3-one 
• 79200-56-9 (-)-2-azabicyclo[2.2.1]hept-5-en-3-one 
• 368870-20-6 5-[(methoxymethylene)amino]-1-[5-O-(tert-butyldimethylsilyl)-2,3-O-(isopropylidene)-β-D-ribofuranosyl]imidazole-4-nitrile 
• 117957-62-7 (1S,3R)-1-amino-3-(hydroxymethyl)cyclopentanone 
• 859147-51-6 N-1-{(1S,4R)-4-(hydroxymethyl)cyclopentyl}-5'-O-(tert-butyldimethylsilyl)-2',3'-O-isopropylideneadenosine 
• 14470-28-1 mono-4-methoxytrityl chloride 

Downstream Products

• 859147-57-2 N-1-[(1S,4R)-4-{(monomethoxytrityl)oxymethyl}cyclopentyl]-5'-O-{bis(phenylthio)phosphoryl}-2',3'-O-isopropylideneadenosine 
• 859147-59-4 N-1-{(1S,4R)-4-(hydroxymethyl)cyclopentyl}-5'-O-{bis(phenylthio)phosphoryl}-2',3'-O-isopropylideneadenosine 
• 859147-55-0 N-1-[(1S,4R)-4-{(monomethoxytrityl)oxymethyl}cyclopentyl]-2',3'-O-isopropylideneadenosine 

Relevant articles and documents

Synthesis of stable and cell-type selective analogues of cyclic ADP-ribose, a Ca2+-mobilizing second messenger. Structure-activity relationship of the N1-ribose moiety

We previously developed cyclic ADP-carbocyclic ribose (cADPcR, 2) as a stable mimic of cyclic ADP-ribose (cADPR, 1), a Ca2+-mobilizing second messenger. A series of the N1-ribose modified cADPcR analogues, designed as novel stable mimics of cAD

Synthesis and biological activity of cyclic ADP-carbocyclic-ribose analogs: Structure-activity relationship and conformational analysis of N-1-carbocyclic-ribose moiety

Several cyclic ADP-carbocyclic-ribose analogs 3-10 modified in the N-1-carbocyclic-ribose moiety were synthesized. Their Ca2+-releasing activity was estimated in sea urchin eggs to show that the 3″-deoxy analog 6 shows 5 times more potent activ