859147-74-3

Upstream product

• 859147-71-0 N-1-[(1R,3S,4R)-3-(monomethoxytrityloxy)-4-{(5-monomethoxytrityl)oxymethyl}cyclopentyl]-5'-O(tert-butyldimethylsilyl)-2',3'-O-isopropylideneadenosine 

Downstream Products

• 859147-81-2 N-1-{(1R,3S,4R)-3-hydroxy-4-(hydroxymethyl)cyclopentyl}-5'-O-{bis(phenylthio)phosphoryl}-2',3'-O-isopropylideneadenosine 
• 859147-77-6 N-1-[(1R,3S,4R)-3-(monomethoxytrityloxy)-4-{(5-monomethoxytrityl)oxymethyl}cyclopentyl]-5'-O-{bis(phenylthio)phosphoryl}-2',3'-O-isopropylideneadenosine 

Relevant academic research and scientific papers

Synthesis of stable and cell-type selective analogues of cyclic ADP-ribose, a Ca2+-mobilizing second messenger. Structure-activity relationship of the N1-ribose moiety

We previously developed cyclic ADP-carbocyclic ribose (cADPcR, 2) as a stable mimic of cyclic ADP-ribose (cADPR, 1), a Ca2+-mobilizing second messenger. A series of the N1-ribose modified cADPcR analogues, designed as novel stable mimics of cAD