859233-91-3

Upstream product

• 79048-33-2 1-[4-(tributylstannyl)phenyl]ethan-1-one 
• 91085-40-4 3-acetoxy-(17α,20Z)-21-(iodo)-19-norpregna-1,3,5(10),20-tetraene-17β-ol 
• 134970-25-5 3-acetoxy-17α-(Z)-<2-(tri-n-butylstannyl)ethenyl>estra-1,3,5(10)-trien-17β-ol 

Relevant academic research and scientific papers

Synthesis and evaluation of (17α,20Z)-21-(4-substituted-phenyl)-19- norpregna-1,3,5(10),20-tetraene-3,17β-diols as ligands for the estrogen receptor-α hormone binding domain: Comparison with 20E-isomers

As part of our ongoing program to develop probes for the hormone binding domain of the estrogen receptor-α (ERα), we prepared and evaluated a series of 17α,Z-(4-substituted-phenyl)-vinyl estradiol derivatives. The results indicated that the relative bindi