CREMOPHOR (R) A6, also known as Cremophor A6, is a nonionic surfactant that is widely utilized in pharmaceutical and cosmetic formulations. It is a mixture of polyethoxylated castor oil and serves as an emulsifier, solubilizer, and stabilizer for various active ingredients. CREMOPHOR (R) A6 enhances the solubility and bioavailability of poorly water-soluble drugs, making it a valuable component in oral and parenteral drug delivery systems. Furthermore, it is also employed in topical formulations, such as creams and lotions, to improve the dispersion and penetration of active ingredients.
85941-44-2
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Basic information
- Product Name: CREMOPHOR (R) A6
- Synonyms: cremophor a6;polyethylene glycol 260mono(hexadecyl/octadecyl)ether and 1-octadecanol
- CAS NO:85941-44-2
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: ethanol: 1 g/10 mL, clear, colorless
- CAS DataBase Reference: CREMOPHOR (R) A6(CAS DataBase Reference)
- NIST Chemistry Reference: CREMOPHOR (R) A6(85941-44-2)
- EPA Substance Registry System: CREMOPHOR (R) A6(85941-44-2)
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Safety Data
- Hazard Codes: Xi
- Statements: 38
- Safety Statements: 37
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 85941-44-2(Hazardous Substances Data)
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85941-44-2 Usage
Uses
Used in Pharmaceutical Industry:CREMOPHOR (R) A6 is used as an emulsifier for improving the stability and solubility of poorly water-soluble drugs, which is crucial for the development of oral and parenteral drug delivery systems.
CREMOPHOR (R) A6 is used as a solubilizer to increase the bioavailability of drugs with low water solubility, thus enhancing their therapeutic effectiveness.
CREMOPHOR (R) A6 is used as a stabilizer to maintain the uniformity and prevent the separation of drug components in pharmaceutical formulations.
Used in Cosmetic Industry:
CREMOPHOR (R) A6 is used as a solubilizer for incorporating active ingredients with low water solubility into cosmetic formulations, such as creams and lotions.
CREMOPHOR (R) A6 is used as an emulsifier to stabilize oil-in-water or water-in-oil emulsions in cosmetic products, ensuring a smooth texture and consistent performance.
CREMOPHOR (R) A6 is used as a stabilizer to maintain the integrity and prolong the shelf life of cosmetic formulations by preventing the separation of ingredients.
Check Digit Verification of cas no
The CAS Registry Mumber 85941-44-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,9,4 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.Calculate Digit Verification of CAS Registry Number 85941-44:
(7*8)+(6*5)+(5*9)+(4*4)+(3*1)+(2*4)+(1*4)=162
162 % 10 = 2
So 85941-44-2 is a valid CAS Registry Number.
85941-44-2Upstream product
85941-44-2Downstream Products
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CREMOPHOR (R) A6
