85944-90-7

Upstream product

• 108-86-1 bromobenzene 
• 5259-65-4 4-methyl-3-cyclohexen-1-one 
• 78012-35-8 (1R,4R)-3-Benzenesulfonyl-4-methyl-cyclohex-2-enol 
• 591-51-5 phenyllithium 
• 20023-36-3 2,5-dihydro-4-methylanisole 

Relevant academic research and scientific papers

Palladium-catalyzed γ-arylation of β,γ-unsaturated ketones: Application to a one-pot synthesis of tricyclic indolines

(Chemical Equation Presented) Indolines in short order: A catalyst system which allows for efficient γ-arylation of β,γ-unsaturated ketones is described (see scheme; dippf = 1,1′-bis(diisopropylphosphanyl) ferrocene, dba = trans,transdibenzylideneacetone). This method can be applied to a one-pot, two-step synthesis of polycyclic indolines from simple starting materials.

Strategic Synthesis based on Cyclohexadienes: Preparation of 2-, 2,3- and 2,4-Substituted Cyclohexenones; Synthesis of (Z)-Heneicosa-6-en-11-one

The mesomeric anions, generated from 1-methoxycyclohexa-1,4-diene, 1-methoxy-5-methylcyclohexa-1,4-diene, and 1-methoxy-4-methylcyclohexa-1,4-diene with potassium amide in liquid ammonia, have been readily alkylated and the resulting dienes were hydrolysed to yield 2-alkyl-, 2,3-dialkyl- and 2,4-dialkyl-cyclohex-2-enones in good yield.Arylation of the above mesomeric anions followed by hydrolysis afforded 2-arylcyclohex-2-enones in addition to substituted biphenyls.A new and efficient synthesis of the male sex attractant of the Douglas Fir Tussock Moth, (Z)-heneicosa-6-en-11-one is described using the above methodology.