85960-27-6

Upstream product

• 85960-26-5 (3S,4R)-1-(tert-Butyl-dimethyl-silanyl)-4-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-3-(1-hydroxy-ethyl)-azetidin-2-one 
• 4457-32-3 4-nitrobenzyl chloroformate 
• 85960-25-4 (3S,4R)-3-Acetyl-1-(tert-butyl-dimethyl-silanyl)-4-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-azetidin-2-one 
• 80559-22-4 (4R)-4-(2-hydroxyethyl)-2-azetidinone 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 77881-95-9 (4S)-4-(methoxycarbonylmethyl)-azetidine-2-one 
• 88649-80-3 (4S)-1-(t-butyldimethylsilyl)-4-(methoxycarbonylmethyl)-azetidine-2-one 
• 87829-35-4 (R)-1-(tert-Butyl-dimethyl-silanyl)-4-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-azetidin-2-one 
• 88649-81-4 (R)-1-(tert-Butyl-dimethyl-silanyl)-4-(2-hydroxy-ethyl)-azetidin-2-one 

Downstream Products

• 64066-69-9 (3S,4R)-4-(2-hydroxyethyl)-3-[(1R)-1-p-nitrobenzyloxycarbonyloxyethyl]-azetidin-2-one 

Relevant academic research and scientific papers

A GENERAL APPROACH TO TRANS-CARBAPENEM ANTIBIOTICS. ENANTIOSELECTIVE SYNTHESIS OF KEY INTERMEDIATES FOR (+)-PS-5, (+)-PS-6, AND (+)-THIENAMYCIN

(S)-4--2-azetidinone prepared by chemico-enzymatic approach has been efficiently converted to key intermediates for the synthesis of natural trans-carbapenem antibiotics, (+)-PS-5, (+)-PS-6, and (+)-thienamycin.