859732-53-9Relevant academic research and scientific papers
INHIBITION OF OLIG2 ACTIVITY
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Paragraph 00419-00420, (2017/04/19)
Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of Olig2. Also described herein are methods of using such Olig2 inhibitors, alone and in combination with other compounds, for treating ca
Synthesis and structure activity relationship of guanidines as NPY Y5 antagonists
Aquino, Christopher J.,Ramanjulu, Joshi M.,Heyer, Dennis,Daniels, Alejandro J.,Palazzo, Fabio,Dezube, Milana
, p. 2691 - 2708 (2007/10/03)
A series of bis-aryl substituted guanidines have been discovered as potent NPY Y5 antagonists. The SAR and in vitro metabolic stability of these compounds are discussed.
