859846-07-4

Basic information

• Product Name: (R)-(-)-1-[(2-methoxy-5-methyl)phenyl]-2-phenylethylamine
• Synonyms: (R)-(-)-1-[(2-methoxy-5-methyl)phenyl]-2-phenylethylamine
• CAS NO: 859846-07-4
• Molecular Weight: 241.333
• Mol File: 859846-07-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-(-)-1-[(2-methoxy-5-methyl)phenyl]-2-phenylethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-1-[(2-methoxy-5-methyl)phenyl]-2-phenylethylamine(859846-07-4)
• EPA Substance Registry System: (R)-(-)-1-[(2-methoxy-5-methyl)phenyl]-2-phenylethylamine(859846-07-4)

Safety Data

• Hazardous Substances Data: 859846-07-4(Hazardous Substances Data)

Upstream product

• 114508-52-0 1-(2-methoxy-5-methyl)-2-phenylethylamine 

Downstream Products

• 946838-81-9 2-((R)-1-amino-2-phenylethyl)-4-methylphenol 

Relevant articles and documents

Synthesis of novel chiral 1,3-aminophenols and application for the enantioselective addition of diethylzinc to aldehydes

Novel chiral 1,3-aminophenols were efficiently synthesized by applying a Friedel-Crafts reaction and optical resolution. The catalytic activity of the aminophenols was studied for the addition of diethylzinc to benzaldehyde. The results showed that (S)-5a with bulky tert-butyl groups on the stereogenic carbon atom and 4,6-positions of phenol favored higher enantioselectivity (94% ee). The same ligand was also used with other aldehydes, to give optically active alcohols in good chemical yields and ee values (up to 99%).