859854-85-6

Basic information

• Product Name: C₈H₁₄BrNO₃
• CAS NO: 859854-85-6
• Molecular Weight: 252.108
• Mol File: 859854-85-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₈H₁₄BrNO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₈H₁₄BrNO₃(859854-85-6)
• EPA Substance Registry System: C₈H₁₄BrNO₃(859854-85-6)

Safety Data

• Hazardous Substances Data: 859854-85-6(Hazardous Substances Data)

Upstream product

• 66643-46-7 ethyl 4-bromo-3-hydroxypiperidine-1-carboxylate 

Relevant articles and documents

PYRROLOTRIAZINE COMPOUNDS AS KINASE INHIBITORS

The present invention provides compounds of formula (I); and pharmaceutically acceptable salts thereof. The formula (I) compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula (I) compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.