859877-16-0

Basic information

• Product Name: 1H-Benzimidazol-2-amine, 7-bromo-1-methyl-N-[4-(trifluoromethoxy)phenyl]-5-(trifluoromethyl)-
• CAS NO: 859877-16-0
• Molecular Formula: C16H10BrF6N3O
• Molecular Weight: 454.169
• Mol File: 859877-16-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Benzimidazol-2-amine, 7-bromo-1-methyl-N-[4-(trifluoromethoxy)phenyl]-5-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazol-2-amine, 7-bromo-1-methyl-N-[4-(trifluoromethoxy)phenyl]-5-(trifluoromethyl)-(859877-16-0)
• EPA Substance Registry System: 1H-Benzimidazol-2-amine, 7-bromo-1-methyl-N-[4-(trifluoromethoxy)phenyl]-5-(trifluoromethyl)-(859877-16-0)

Safety Data

• Hazardous Substances Data: 859877-16-0(Hazardous Substances Data)

Upstream product

• 113170-71-1 2-bromo-6-nitro-4-(trifluoromethyl)aniline 
• 859877-14-8 (2-bromo-6-nitro-4-trifluoromethyl-phenyl)-methyl-amine 

Downstream Products

• 859877-24-0 1,7-dimethyl-N-[4-(trifluoromethoxy)phenyl]-5-(trifluoromethyl)-1H-benzimidazol-2-amine 
• 859877-22-8 1-methyl-7-(methylsulfonyl)-N-[4-(trifluoromethoxy)phenyl]-5-(trifluoromethyl)-1H-benzimidazol-2-amine 
• 1351646-66-6 C₂₈H₂₅F₆N₃O₄ 
• 859877-17-1 methyl 4-[(4-bromo-6-trifluoromethyl-3-methyl-2-{[4-(trifluoromethoxy)-phenyl]imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]benzoate 
• 859877-18-2 1-methyl-N-[4-(trifluoromethoxy)phenyl]-5-(trifluoromethyl)-7-vinyl-1H-benzimidazol-2-amine 

Relevant articles and documents

Discovery of cyclic guanidines as potent, orally active, human glucagon receptor antagonists

In the course of the development of an aminobenzimidazole class of human glucagon receptor (hGCGR) antagonists, a novel class of cyclic guanidine hGCGR antagonists was discovered. Rapid N-dealkylation resulted in poor pharmacokinetic profiles for the benc