85990-80-3

Upstream product

• 7536-58-5 BOC-L-aspartic acid 4-benzyl ester 
• 23680-31-1 BOC-O-benzyl-L-serine 
• 85990-79-0 t-butoxycarbonyl-L-phenylalanyl-L-asparaginyl-O-benzyl-L-seryl-L-alanine 4-picolyl ester 
• 85990-78-9 t-butoxycarbonyl-L-asparaginyl-O-benzyl-L-seryl-L-alanine 4-picolyl ester 
• 85990-77-8 t-butoxycarbonyl-O-benzyl-L-seryl-L-alanine 4-picolyl ester 
• 64991-56-6 L-alanine 4-picolyl ester 
• 77422-40-3 tert-butyloxycarbonylalanyl-4-pyridylmethylester 

Downstream Products

• 85990-81-4 t-butoxycarbonyl-L-glutaminyl-β-benzyl-L-aspartyl-L-phenylalanyl-L-asparaginyl-O-benzyl-L-seryl-L-alanine 4-picolyl ester 
• 85990-82-5 N,N^Im-di-t-butoxycarbonyl-L-histidyl-L-glutaminyl-β-benzyl-L-aspartyl-L-phenylalanyl-L-asparaginyl-O-benzyl-L-seryl-L-alanine 4-picolyl ester 

Relevant academic research and scientific papers

Amino-acids and Peptides Part 47. Synthesis of Peptides Related to Bovine Prothrombin.

It is known that Fragment 2 of bovine prothrombin inhibits the coagulation of blood plasma, and various considerations suggest that the inhibitory site might be in the 198-215 region (1) of prothrombin.Peptides related to the sequences in the 202-215 region of bovine prothrombin (2) have been synthesised by the picolyl ester method for examination as possible anticoagulation agents, including the bovine fragment 202-215 and the human fragment 204-215, variants of the sequence 210-215, and the bovine and human sequences 202-209.