85992-81-0Relevant articles and documents
Synthesis of benzene-1-alanine-3-glycine as carba analogues of cystine
Furenes, Eline Bredal,Luijendijk, Jaco,Efskind, Jon,Undheim, Kjell
, p. 193 - 200 (2007/10/03)
Methodology has been developed for the synthesis of C4-carba- bridged cystine analogues with a 1,3-disubstituted phenyl group inserted into the chain. Stereoselective bromobenzylation of the Schoellkopf chiron and a subsequent bromine-lithium e
NEW SYNTHESES OF α-AMINO ACIDS BASED ON N-ACYLIMINO ACETATES
Bretschneider, Thomas,Miltz, Wolfgang,Muenster, Peter,Steglich, Wolfgang
, p. 5403 - 5414 (2007/10/02)
The reaction of N-acylamino-2-bromoacetates 2 ( via N-acylimino acetates 3 ) with higher order mixed cuprates, trimethylsilyl enol ethers and β-dicarbonyl compounds leads to a variety of α-amino acid derivatives.Their conversion into the free amino acids can be conveniently carried out by the use of t-butyl protection.In case of the N-acetyl compounds cleavage of the protecting group and optical resolution can be achieved in one step hog renal acylase.
Reaction of Acylaminobromomalonates and Acylaminobromoacetates with Trialkylphosphites - A Simple Synthesis of Ethyl 2-Amino-2-(diethoxyphosphoryl)acetate
Kober, Reiner,Steglich, Wolfgang
, p. 599 - 609 (2007/10/02)
Depending on the reaction conditions acylaminobromomalonates 1 and trialkylphosphites yield either 5-alkoxyoxazoles 7, 2-malonates 8, or 2-acylamino-2-(dialkoxyphosphoryl)malonates 2.N-Acylglucin esters 9 can be converted in
