86012-92-2Relevant academic research and scientific papers
Synthesis of Alkylpyrroles by the Sodium Borohydride Reduction of Acylpyrroles
Greenhouse, Robert,Ramirez, Coral,Muchowski, Joseph M.
, p. 2961 - 2965 (2007/10/02)
N-Unsubstituted alkylpyrroles are obtained by the reduction of the corresponding acylpyrroles with sodium borohydride in boiling 2-propanol.This reaction was demonstrated to proceed via the pyrrolylalkylcarbinol and was extended to the synthesis of a branched chain alkylpyrrole 25 from the tertiary alcohol 24.
Diels-Alder Reactions of Vinyl Derivatives of Five-Membered Monoheterocyclic Compounds
Noland, Wayland E.,Lee, Chang Kiu,Bae, Sun Kun,Chung, Bong Yul,Hahn, Chi Sun,Kim, Keun Jae
, p. 2488 - 2491 (2007/10/02)
Vinylpyrroles having electron-withdrawing substituents react with dienophiles to give ? adducts while the furan and thiophene analogues do not.The difference in reactivity among the monoheterocycles can be explained in terms of the greater electron-releasing ability of the nitrogen atom in the pyrrole.The s-cis conformation of the (1H-pyrrol-2-yl)maleate derivatives appears to be an important factor in their undergoing the cycloaddition reaction.
