860262-06-2

Upstream product

• 455-18-5 4-CF₃C₆H₄CN 
• 39256-35-4 benzyloxyacetic acid hydrazide 

Downstream Products

• 860262-19-7 5-(benzyloxymethyl)-1-methyl-3-[4-(trifluoromethyl)phenyl]-1,2,4-triazole 
• 860262-07-3 C₁₉H₁₈F₃N₃O 
• 860262-20-0 [2-methyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-triazol-3-yl]methanol 

Relevant academic research and scientific papers

NOVEL PIPERIDINE DERIVATIVES

The invention relates to a compound of formula (I) wherein A1, A2 and R1to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.

TRIAZOLE, OXADIAZOLE AND THIADIAZOLE DERIVATIVE AS PPAR MODULATORS FOR THE TREATMENT OF DIABETES

The present invention is directed to compounds represented by the following structural formula, Formula (I): wherein: (a) X is selected from the group consisting of a single bond, O, S, S(O)2 and N; (b) U is an aliphatic linker; (c) Y is selected from the group consisting of O, C, S, NH and a single bond; (d) W is N, O or S; (e) E is C(R3)(R4)A or A and wherein; (f) A is selected from the group consisting of carboxyl, tetrazole, C1-C6 alkylnitrile, carboxamide, sulfonamide and acylsufonamide. The other substituents are defined in the claims; the compounds are modulators of peroxisome proleferator activated receptors (PPARs) and are useful for the treatment of diabetes and other metabolic disorders.