860293-78-3Relevant academic research and scientific papers
Palladium-catalyzed cross-coupling reactions of 7-bromo-2,3-diphenyl- pyrido[2,3-b]pyrazine
Yin, Lunxiang,Liebscher, Juergen
, p. 1345 - 1349 (2007/10/03)
First examples of palladium-catalyzed cross-coupling reactions, such as Suzuki, Sonogashira, Heck and Buchwald-Hartwig reactions, are reported in the pyrido[2,3-b]pyrazine series. This methodology circumvents problems found in uncatalyzed nucleophilic sub
New calcineurin inhibiting 3-dimethylaminopropyl substituted diarylheterocycles by sonogashira reactions and catalytic hydrogenation
Yin, Lunxiang,Erdmann, Frank,Liebscher, Juergen
, p. 1369 - 1379 (2007/10/03)
A series of calcineurin inhibiting compounds 1 consisting of a central aromatic N-heterocycle, two aryl substituents and a 3-dimethylaminopropyl chain was synthesized by introduction of the side chain. A corresponding haloheterocycle 3 was transformed int
