86042-28-6

Basic information

• Product Name: 1,5-Di-O-(4-methylbenzoyl)-2,3-O-isopropylidene-beta-D-ribofuranose
• Synonyms: 1,5-DI-O-(4-METHYLBENZOYL)-2,3-O-ISOPROPYLIDENE-BETA-D-RIBOFURANOSE;1,5-Di-O-(4-methylbenzoyl)-2,3-O-isopropylidene-β-D-ribofuranose;(3aR,4S,6R,6aR)-2,2-dimethyl-6-((4-methylbenzoyloxy)methyl)tetrahydrofuro[3,4-d][1,3]dioxol-4-yl 4-methylbenzoate;1,5-Di-O-toluoyl-2,3-O-isopropylidene-b-D-ribofuranose
• CAS NO: 86042-28-6
• Molecular Formula: C₂₄H₂₆O₇
• Molecular Weight: 426.46
• Mol File: 86042-28-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 541.3 °C at 760 mmHg
• Flash Point: 233.6 °C
• Appearance: /
• Density: 1.27 g/cm³
• Refractive Index: 1.583
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1,5-Di-O-(4-methylbenzoyl)-2,3-O-isopropylidene-beta-D-ribofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-Di-O-(4-methylbenzoyl)-2,3-O-isopropylidene-beta-D-ribofuranose(86042-28-6)
• EPA Substance Registry System: 1,5-Di-O-(4-methylbenzoyl)-2,3-O-isopropylidene-beta-D-ribofuranose(86042-28-6)

Safety Data

• Hazardous Substances Data: 86042-28-6(Hazardous Substances Data)

Usage

Description

1,5-Di-O-(4-methylbenzoyl)-2,3-O-isopropylidene-beta-D-ribofuranose is a complex chemical compound derived from ribofuranose, a type of sugar. It features two 4-methylbenzoyl groups and an isopropylidene group, which contribute to its unique chemical properties. 1,5-Di-O-(4-methylbenzoyl)-2,3-O-isopropylidene-beta-D-ribofuranose has garnered interest in the fields of organic synthesis and medicinal chemistry due to its potential applications in the development of new drugs and as a building block for synthesizing other organic compounds.

Uses

Used in Organic Synthesis:
1,5-Di-O-(4-methylbenzoyl)-2,3-O-isopropylidene-beta-D-ribofuranose is used as a key intermediate in organic synthesis for the creation of various organic compounds. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1,5-Di-O-(4-methylbenzoyl)-2,3-O-isopropylidene-beta-D-ribofuranose is used as a potential building block for the development of new drugs. Its chemical properties may contribute to the design of novel pharmaceuticals with improved efficacy and selectivity.
Used in Pharmaceutical Industry:
1,5-Di-O-(4-methylbenzoyl)-2,3-O-isopropylidene-beta-D-ribofuranose is used as a precursor in the pharmaceutical industry for the synthesis of drug candidates. Its unique structure and reactivity make it a promising candidate for the development of innovative therapeutic agents.
Used in Research and Development:
1,5-Di-O-(4-methylbenzoyl)-2,3-O-isopropylidene-beta-D-ribofuranose is also used in research and development settings to explore its potential applications and properties further. Scientists and chemists investigate its reactivity, stability, and interactions with other molecules to uncover new ways to utilize it in various chemical and pharmaceutical processes.

InChI:InChI=1/C24H26O7/c1-14-5-9-16(10-6-14)21(25)27-13-18-19-20(31-24(3,4)30-19)23(28-18)29-22(26)17-11-7-15(2)8-12-17/h5-12,18-20,23H,13H2,1-4H3/t18-,19-,20-,23+/m1/s1

Upstream product

• 67814-68-0 2,3-O-isopropylidene-D-ribofuranose 
• 874-60-2 4-methyl-benzoyl chloride 

Downstream Products

• 86042-31-1 1,2,3-tri-O-p-nitrobenzoyl-5-O-p-toluyl-β-D-ribofuranose 
• 86042-32-2 1,2,3-tri-O-benzoyl-5-O-p-toluyl-β-D-ribofuranose 
• 98807-29-5 4-Methyl-benzoic acid (3aR,4R,6S,6aR)-6-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester 
• 98807-33-1 4-Methyl-benzoic acid (3aR,4R,6R,6aR)-6-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester 
• 98807-29-5 4-Methyl-benzoic acid (3aR,4R,6aR)-6-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester 
• 98807-28-4 4-Methyl-benzoic acid (3aR,4R,6aR)-6-(4-hydroxy-5-methyl-2-oxo-2H-pyrimidin-1-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester 
• 98807-27-3 4-Methyl-benzoic acid (3aR,4R,6S,6aR)-6-(4-hydroxy-2-oxo-2H-pyrimidin-1-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester 
• 98807-31-9 4-Methyl-benzoic acid (3aR,4R,6R,6aR)-6-(4-hydroxy-2-oxo-2H-pyrimidin-1-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester 
• 98807-27-3 4-Methyl-benzoic acid (3aR,4R,6aR)-6-(4-hydroxy-2-oxo-2H-pyrimidin-1-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester 
• 86042-29-7 1,2,3-tri-O-acetyl-5-O-p-toluyl-β-D-ribofuranose 

Relevant articles and documents

IMPROVED SYNTHESIS OF 2,5-ANHYDRO-D-ALLONITRILE

Two types of mixed ester of β-D-ribofuranose were synthesized.The first had the same groups attached to O-1, 2, and 3, and the second had the same groups attached to O-2,3 and 5.The three esters obtained in the highest yields, starting from D-ribose, were then converted into the halides and nitriles.Of the esters studied, the best suited for conversion into the nitrile was 1-O-acetyl-2,3,5-tri-O-p-toluyl-β-D-ribofuranose, which afforded 2,5-anhydro-3,4,6-tri-O-p-toluyl-D-allonitrile in 60percent yield.