86042-35-5Relevant articles and documents
IMPROVED SYNTHESIS OF 2,5-ANHYDRO-D-ALLONITRILE
El Khadem, Hassan S.,Kawai, Joshua
, p. 131 - 138 (2007/10/02)
Two types of mixed ester of β-D-ribofuranose were synthesized.The first had the same groups attached to O-1, 2, and 3, and the second had the same groups attached to O-2,3 and 5.The three esters obtained in the highest yields, starting from D-ribose, were then converted into the halides and nitriles.Of the esters studied, the best suited for conversion into the nitrile was 1-O-acetyl-2,3,5-tri-O-p-toluyl-β-D-ribofuranose, which afforded 2,5-anhydro-3,4,6-tri-O-p-toluyl-D-allonitrile in 60percent yield.