86043-98-3Relevant academic research and scientific papers
SYNTHESIS OF 1-HYDROXYAZETIDINES AND THEIR CONVERSION INTO 1,4-DIACETOXY-2-AZETIDINONES
Pennings, M.L.M.,Kuiper, D.,Reinhoudt, D.N.
, p. 825 - 828 (2007/10/02)
1-Hydroxyazetidines (5), prepared by reductive cyclization of O-benzyl-β-tosyloxy oximes 1 and subsequent debenzylation, can be oxidized selectively either to four-membered cyclic nitrones (6 and 7) or to 1,4-diacetoxy-2-azetidinones (9).
Chemistry of Four-Membered Cyclic Nitrones. 5. Synthesis and Oxidation of 1-Hydroxyazetidines
Pennings, Marcel L. M.,Reinhoudt, David N.
, p. 4043 - 4048 (2007/10/02)
1-(Benzyloxy)azetidines 9 are prepared by reductive cyclization of the corresponding O-benzyl oximes (6) that have a leaving group at the β-position.Reduction of the unprotected oxime 6a with sodium cyanoborohydride in acetic acid affords 3,4,4-trimethyli
