86044-23-7Relevant academic research and scientific papers
Carboxylate-substituted Nitrones as Aldehyde Synthons for the Addition of Ketone Enolates
Schlecht, Matthew F.
, p. 1239 - 1241 (2007/10/02)
The addition of a ketone enolate to an ester-substituted nitrone gives an adduct, which upon Hofmann degradation can be elaborated to give a γ-keto-α,β-unsaturated ester, the formal product of a directed aldol condensation.
THE METHOXYCARBONYLALKYLATION AND METHOXYCARBONYLALKYLIDENATION OF SILYL ENOL ETHERS
Fleming, Ian,Iqbal, Javed
, p. 327 - 328 (2007/10/02)
Silyl enol ethers (1) react with the phenylthio(methoxycarbonyl)alkyl chlorides (2) in the presence of Lewis acids to give good yields of the γ-ketoesters (3); oxidative and reductive desulphurisations give the saturated (4) and unsaturated (5 or 6) γ-ket
