86046-50-6

Basic information

• Product Name: 4,5-methylenedioxy-4'-hydroxy-2-aldehyde[1,1'-biphenyl]
• CAS NO: 86046-50-6
• Molecular Weight: 242.231
• Mol File: 86046-50-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,5-methylenedioxy-4'-hydroxy-2-aldehyde[1,1'-biphenyl](CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-methylenedioxy-4'-hydroxy-2-aldehyde[1,1'-biphenyl](86046-50-6)
• EPA Substance Registry System: 4,5-methylenedioxy-4'-hydroxy-2-aldehyde[1,1'-biphenyl](86046-50-6)

Safety Data

• Hazardous Substances Data: 86046-50-6(Hazardous Substances Data)

Upstream product

• 507-79-9 tazettine 
• 71597-85-8 (p-hydroxyphenyl)boronic acid 
• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 

Relevant articles and documents

Asymmetric Synthesis of Cyclohexenone-Fused Isochromans via Quinidine-Catalyzed Domino Peroxyhemiacetalization/Oxa-Michael Addition/Desymmetrization Sequence

A highly enantio- and diastereoselective synthesis of highly functionalized isochromans was achieved through an organocatalyzed domino reaction. Quinidine as the catalyst initiates a peroxyhemiacetalization/oxa-Michael/desymmetrization domino sequence between various 2,5-cyclohexadienone-tethered aryl aldehydes with hydroperoxides to generate the single diastereomers of isochromans appended with a cyclohexenone ring bearing three vicinal stereocenters in good yields and high enantioselectivities under ambient reaction conditions.