860466-44-0Relevant academic research and scientific papers
Structure-Activity Relationship Study of Amidobenzimidazole Analogues Leading to Potent and Systemically Administrable Stimulator of Interferon Gene (STING) Agonists
Song, Zilan,Wang, Xiyuan,Zhang, Yan,Gu, Wangting,Shen, Ancheng,Ding, Chunyong,Li, Han,Xiao, Ruoxuan,Geng, Meiyu,Xie, Zuoquan,Zhang, Ao
, p. 1649 - 1669 (2021)
Activation of the stimulator of interferon gene (STING) has emerged as an exciting immuno-oncology therapeutic strategy; however, the first-generation STING agonists, cyclic dinucleotide (CDN) analogues, have suffered from many disadvantages and failed in
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A compound of formula (I) or a pharmaceutically acceptable salt or prodrug ester thereof; wherein R1-R7 are as disclosed in the specification and pharmaceutical uses thereof.
