86061-91-8

Upstream product

• 15500-60-4 N,N-bis(trimethylsilyl)formamide 
• 93521-25-6 C₁₉H₁₈Cl₃F₃N₂O₇S₂ 
• 93521-25-6 benzyl 6β-penicillanate 
• 93553-10-7 benzyl 6β-penicillanate 
• 93553-04-9 benzyl 6β-penicillanate 
• 82954-45-8 benzyl 6β-(N-trifluoromethylsulphonylamino)penicillanate 
• 93553-09-4 benzyl 6β-(2,4,5-trichlophenylsulphonylamino)penicillanate 
• 93553-03-8 benzyl 6β-(nonafluorobutylsulphonylamino)penicillanate 
• 2258-42-6 formyl acetic anhydride 
• 3956-31-8 benzyl (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 82954-45-8 (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-trifluoromethanesulfonylamino-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzyl ester 

Downstream Products

• 111969-74-5 benzyl (2R,4S)-5,5-dimethyl-2-(formamido)(methoxycarbonyl)methyl>thiazolidine-4-carboxylate 
• 93521-23-4 benzyl 6α-formamido-6β-(2,2,2-trichloroethoxycarbonylamino)penicillanate 1α-oxide 
• 93521-24-5 benzyl 6β-(2,2,2-trichloroethoxycarbonylamino)-6α-formamidopenicillanate 1β-oxide 
• 49626-61-1 benzyl (4S)-4,5-dihydro-5,5-dimethylthiazole-4-carboxylate 
• 111969-78-9 benzyl (2S)-2-formamido-3-mercapto-3-methylbutanoate 

Relevant academic research and scientific papers

Direct Incorporation of a 6&α(7&α)-Formamido Group into Penicillin and Cephalosporin Sulphides and Sulphoxides

6β(7β)--penicillins and -cephalosporins have been converted into the corresponding 6α(7α)-formamido-6β(7β)-(2,2,2-trichloroethoxycarbonylamino) derivatives by treatment with N,N-bis(trimet

Process for the preparation of β-lactam compounds

A process for the preparation of a β-lactam having the partial structure (I): STR1 wherein R1 is an acyl group, which process comprises treating an imine having the partial structure (II): STR2 with a nucleophilic derivative of formamide.

DIRECT INCORPORATION OF A 6α(7α)-FORMAMIDO GROUP INTO PENICILLINS AND CEPHALOSPORINS

6β(7β)-(N-2,2,2-Trichloroethoxycarbonyl-N-triflouromethanesulphonylamino)penicillins and cephalosporins have been converted into the corresponding 6α(7α)-formamido-6β(7β)-2,2,2-trichloroethoxycarbonylamino deriatives, by treatment with N,N-bis(trimethylsi

β-Lactam antibacterial agents

β-Lactam antibiotics having an α-formamido substituent on the carbon atom adjacent to the carbonyl group of the β-lactam ring and in particular bicyclic compounds having the partial structure: STR1 Intermediates and processes for the preparation of the compounds are further disclosed.