860617-52-3Relevant articles and documents
5-(3-Cyclopentyl-2-thioxo-2,3-dihydro-1H-benzimidazol-5-yl)-1-methyl-1H- pyrrole-2-carbonitrile: A novel, highly potent, selective, and orally active non-steroidal progesterone receptor agonist
Zhang, Puwen,Terefenko, Eugene,Kern, Jeffrey,Fensome, Andrew,Trybulski, Eugene,Unwalla, Ray,Wrobel, Jay,Lockhead, Susan,Zhu, Yuan,Cohen, Jeffrey,LaCava, Margaret,Winneker, Richard C.,Zhang, Zhiming
, p. 6556 - 6564 (2008/09/17)
We have recently discovered 5-(3-cyclopentyl-2-thioxo-2,3-dihydro-1H-benzimidazol-5-yl)-1-methyl-1H- pyrrole-2-carbonitrile (14) as a potent, selective, and orally active non-steroidal progesterone receptor (PR) agonist. Compound 14 and its analog 13 poss