860634-47-5Relevant articles and documents
A C-linked disaccharide analogue of Thomsen-Friedenreich epitope induces a strong immune response in mice
Awad, Loay,Madani, Rime,Gillig, Annabelle,Kolympadi, Maria,Philgren, Maria,Muhs, Andreas,Gerard, Catherine,Vogel, Pierre
, p. 8578 - 8582 (2012/09/21)
Anticancer vaccine: Antigen 2 made out of a tripeptide of β-D-Galp-(1→3)-CH2-α-D-GalNAc-O-Ser and conjugated with keyhole limpet hemocyanin (KLH) protein induced an early and strong immune response (IgG antibodies) in mice. Antigen 3 made out o
C-linked disaccharide analogue of the Thomsen-Friedenreich (T)-epitope α-O-conjugated to L-serine
Awad, Loay,Riedner, Jens,Vogel, Pierre
, p. 3565 - 3573 (2007/10/03)
Condensation of a silylated β-D-galactopyranosylaldehyde (3) with isolevoglucosenone (4) in the presence of Et2AlI provided bicyclic enone 5. Subsequent addition of BnNHOMe gave adduct 6, which was converted into 4-O-acetyl-1,6-anhydro-3-C-[(1R