860770-08-7Relevant academic research and scientific papers
Ring-closing metathesis (RCM) for the synthesis of cyclic sulfoximines
Bolm, Carsten,Villar, Helene
, p. 1421 - 1424 (2005)
Chiral heterocycles can be prepared starting from doubly unsaturated sulfoximine derivatives by ring-closing metathesis reaction in good yields. Georg Thieme Verlag Stuttgart.
N-alkylations of NH-sulfoximines and NH-sulfondiimines with alkyl halides mediated by potassium hydroxide in dimethyl sulfoxide
Hendriks, Christine M. M.,Bohmann, Rebekka A.,Bohlem, Marina,Bolm, Carsten
supporting information, p. 1847 - 1852 (2014/06/09)
A general method for the N-alkylation of NH-sulfoximines and NH-sulfondiimines has been developed, employing alkyl bromides with KOH in DMSO at room temperature. A variety of previously inaccessible N-alkylated sulfoximines and sulfondiimines was prepared in good to excellent yields (up to 97%). As an application, the conditions were used to access the biologically active Suloxifen.
