861040-36-0Relevant academic research and scientific papers
Arene chromium tricarbonyl catalyzed reactions in organic synthesis
Sodeoka,Shibasaki
, p. 643 - 658 (1993)
Arene chromium tricarbonyl complexes have been widely used in synthetic organic chemistry. In this article, catalytic activities of these complexes in hydrogenation and isomerization are discussed. Furthermore, their application to the syntheses of biologically significant compounds such as prostaglandins, sex pheromones and antitumor antibiotics is also reviewed.
Direct reductive amination of aldehydes using lithium-arene(cat.) as reducing system. A simple one-pot procedure for the synthesis of secondary amines
Nador, Fabiana,Moglie, Yanina,Ciolino, Andrés,Pierini, Adriana,Dorn, Viviana,Yus, Miguel,Alonso, Francisco,Radivoy, Gabriel
experimental part, p. 3156 - 3160 (2012/08/08)
A simple one-pot procedure for the direct reductive amination of aldehydes using lithium powder and a catalytic amount of 4,4′-di-tert-butylbiphenyl (DTBB) or a polymer supported naphthalene as reducing system is described. The direct reductive amination of a variety of aldehydes with primary amines was achieved simply by adding a mixture of the corresponding carbonyl compound and the amine, over a solution of the lithium arenide in THF at room temperature. For most of the substrates tested the main reaction products were the secondary amines along with variable amounts of the corresponding alcohol and/or imine products. Theoretical DFT calculations have been applied in order to explain the differences in reactivity observed for aromatic substrates.
