861146-14-7Relevant articles and documents
Optimization of anti-Trypanosoma cruzi oxadiazoles leads to identification of compounds with efficacy in infected mice
Dos Santos Filho, Jose Mauricio,Moreira, Diogo Rodrigo M.,De Simone, Carlos Alberto,Ferreira, Rafaela Salgado,McKerrow, James H.,Meira, Cassio Santana,Guimaraes, Elisalva Teixeira,Soares, Milena Botelho Pereira
, p. 6423 - 6433,11 (2012)
We recently showed that oxadiazoles have anti-Trypanosoma cruzi activity at micromolar concentrations. These compounds are easy to synthesize and show a number of clear and interpretable structure-activity relationships (SAR), features that make them attr
