861221-67-2Relevant academic research and scientific papers
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: Synthesis, biological evaluation and 3D-QSAR investigation
Selleri, Silvia,Gratteri, Paola,Costagli, Camilla,Bonaccini, Claudia,Costanzo, Annarella,Melani, Fabrizio,Guerrini, Gabriella,Ciciani, Giovanna,Costa, Barbara,Spinetti, Francesca,Martini, Claudia,Bruni, Fabrizio
, p. 4821 - 4834 (2007/10/03)
The present paper reports the synthesis and binding studies of new 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as selective Peripheral Benzodiazepine Receptor (PBR) ligands. The variability of substituents at the 3-position was investigated and a 3D-
