861238-38-2Relevant academic research and scientific papers
Human skin permeation of branched-chain 3-O-alkyl ester and carbonate prodrugs of naltrexone
Vaddi, Haranath K.,Hamad, Mohamed O.,Chen, Jianhong,Banks, Stan L.,Crooks, Peter A.,Stinchcomb, Audra L.
, p. 758 - 765 (2005)
Purpose. Physicochemical characterization and in vitro human skin diffusion studies of branched-chain ester and carbonate prodrugs of naltrexone (NTX) were compared and contrasted with straight-chain ester and carbonate NTX prodrugs. Methods. Human skin p
SYNTHESIS OF (R)-N-METHYLNALTREXONE
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Page/Page column 57-58; 4/6, (2010/11/25)
This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.
