861239-99-8Relevant articles and documents
A convenient synthesis of N-aryl benzamides by rhodium-catalyzed ortho-amidation and decarboxylation of benzoic acids
Shi, Xian-Ying,Liu, Ke-Yan,Fan, Juan,Dong, Xue-Fen,Wei, Jun-Fa,Li, Chao-Jun
, p. 1900 - 1903 (2015)
The rhodium-catalyzed amidation of substituted benzoic acids with isocyanates by directed C-H functionalization followed by decarboxylation to afford the corresponding N-aryl benzamides is demonstrated, in which the carboxylate serves as a unique, removable directing group. Notably, less common meta-substituted N-aryl benzamides are generated readily from more accessible paraor ortho-substituted groups by employing this strategy.