86130-01-0Relevant academic research and scientific papers
Diastereoselective aminooxygenation and diamination of alkenes with amidines by hypervalent Iodine(III) reagents
Chen, Hui,Kaga, Atsushi,Chiba, Shunsuke
, p. 6136 - 6139 (2014)
Diastereoselective anti-aminooxygenation and anti-diamination of alkenes with amidines were enabled by hypervalent iodine(III) reagents such as PhI(OCOR)2 and PhI(NMs2)2, respectively. The present transformation offers diastereochemically pure dihydroimidazoles divergently from E- and Z-alkenes.
Ytterbium triflate catalyzed synthesis of alkoxy-substituted donor-acceptor cyclobutanes and their formal [4 + 2] cycloaddition with imines: Stereoselective synthesis of piperidines
Moustafa, Mahmoud M. Abd Rabo,Pagenkopf, Brian L.
supporting information; experimental part, p. 4732 - 4735 (2010/12/25)
A new synthesis of 2-alkoxy-1,1-cyclobutane diesters and their first use in dipolar cycloadditions is reported. Both the formation of the donor-acceptor cyclobutanes and their subsequent annulation with in situ formed imines are catalyzed by Yb(OTf)3
Halogenated Ketenes. 38. Cycloaddition of α,β-Unsaturated Imines with Ketenes To Yield Both β- and δ-Lactams
Brady, William T.,Shieh, C. H.
, p. 2499 - 2502 (2007/10/02)
The cycloaddition of various types of α,β-unsaturated imines with diphenyl- and dichloroketenes yields both (2 + 2) and (4 + 2) cycloaddition products, i. e., β-lactams and δ-lactams, respectively.The cycloaddition products are dependent upon substitution in the imine and the ketene.The δ-lactams derived from dichloroketene are easily dehydrochlorinated to the corresponding 2-pyridones.All of the results are consistent with a two-step cycloaddition process involving a dipolar intermediate.
