86132-70-9Relevant academic research and scientific papers
Total synthesis of (-)-Lepistine
Kitabayashi, Yusuke,Yokoshima, Satoshi,Fukuyama, Tohru
supporting information, p. 2862 - 2864 (2014/06/23)
The first total synthesis of (-)-lepistine has been accomplished in 11 steps from (S)-glycidol. The synthesis features construction of the 10-membered ring via an intramolecular epoxide opening by nosylamide, regioselective dehydration to form an enol eth
Optical isomers, processes for production thereof and pharmaceutical composition thereof
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, (2008/06/13)
An optical isomer selected from the group consisting of (2'R),(3R)-3,4-dihydro-8-(2'-hydroxy-3'-isopropylamino)propoxy-3-nitroxy-2H-1-benzopyran, (2'S),(3R)-3,4-dihydro-8-(2'-hydroxy-3'-isopropylamino)propoxy-3-nitroxy-2H-1-benzopyran and acid addition salts of these isomers, process for producing these isomers and a pharmaceutical composition thereof useful for the treatment of cardiovascular diseases.
