861343-73-9 Usage
General Description
BenzenaMine, 2-[(1-Methylethyl)thio]-, hydrochloride (1:1) is a chemical compound with distinct properties. It is mainly identified by its chemical name and is recognized due to its unique structure which contains a benzene ring, an amine group, a 1-methylethyl thio group attached to the benzene, and a hydrochloride. The hydrochloride indicates that it exists as a salt, which often provides improved water solubility. This substance is likely used in various industrial applications, including the field of organic synthesis, and may also be involved in pharmaceutical development processes. As with any chemical, it should be handled with care to avoid potential health hazards. Specific safety and handling data would be obtained from its Material Safety Data Sheet (MSDS).
Check Digit Verification of cas no
The CAS Registry Mumber 861343-73-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,1,3,4 and 3 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 861343-73:
(8*8)+(7*6)+(6*1)+(5*3)+(4*4)+(3*3)+(2*7)+(1*3)=169
169 % 10 = 9
So 861343-73-9 is a valid CAS Registry Number.
861343-73-9Relevant articles and documents
Anti-cancer drug ceritinib intermediate 1-amino-2-(isopropyl sulfonyl)benzene synthetic method
-
Paragraph 0026-32, (2017/07/21)
The invention belongs to the technical field of medicine synthesis, and especially relates to a synthetic method of an anti-cancer drug ceritinib intermediate 1-amino-2-(isopropyl sulfonyl)benzene. The synthetic method comprises the following steps: employing o-fluoronitrobenzene, sodium hydride and isopropyl mercaptan to synthesize a 2-(isopropyl sulfide) nitrobenzene crude product, then directly reducing the crude product to iron powder, forming salt to obtain the 2-(isopropyl sulfide) aniline hydrochloride, and finally dropping hydrogen peroxide for oxidation in 2-(isopropyl sulfide) aniline hydrochloride for oxidation, forming salt, and dissociating to obtain a target product. The synthetic method has the advantages of simpleness, little sewage amount, low energy consumption, low production cost, and the product has the advantages of high purity, high yield, and easy industrial production, and is suitable for further popularization and application.
