861389-38-0Relevant articles and documents
Palladium-catalyzed sequential alkylation-alkenylation reactions: Application towards the synthesis of polyfunctionalized fused aromatic rings
Alberico, Dino,Paquin, Jean-Fran?ois,Lautens, Mark
, p. 6283 - 6297 (2005)
The synthesis of polyfunctionalized fused aromatic carbo- and heterocycles from aryl iodides and bromoenoates via a tandem palladium-catalyzed aromatic substitution intramolecular Heck sequence is reported. Using Pd(OAc)2 and tri-2-furylphosphine (TFP) in the presence of norbornene and Cs 2CO3 in CH3CN at 85°C gave a variety of functionalized bi- and tricyclic fused aromatic rings in good yield.