86139-08-4

Upstream product

• 86138-88-7 (2R,3R,6S)-3-Hydroxy-6-((R)-2-hydroxy-2-phenyl-ethyl)-2-prop-1-ynyl-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 86138-88-7 (2R,3R,6S)-3-Hydroxy-6-((S)-2-hydroxy-2-phenyl-ethyl)-2-prop-1-ynyl-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 86138-85-4 (2R,3S,6S)-3-Hydroxy-6-(2-oxo-2-phenyl-ethyl)-2-prop-1-ynyl-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 86138-81-0 (2R,6S)-3-Oxo-6-(2-oxo-2-phenyl-ethyl)-2-prop-1-ynyl-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 

Relevant academic research and scientific papers

APPLICATION OF THE OXYGENATIVE NUCLEOPHILE INTRODUCTION REACTION TO 1-ALKOXYCARBONYL-2-ALKYNYL-1,2-DIHYDROPYRIDINES. A FACILE SYNTHESIS OF (+/-)-SEDACRYPTINE

A Sedum alkaloid, (+/-)-sedacryptine (17) was effectively synthesized from the compound (3g), one of the products (3a-3l) derived from 2-alkynyl-1,2-dihydropyridine derivatives (2) by application of our oxygenative nucleophile introduction reaction.