861393-60-4Relevant academic research and scientific papers
Cyanoamidine P2X7 antagonists for the treatment of pain
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Page/Page column 16, (2008/06/13)
Novel cyanoamidines compounds of formula (I) and (II) and their derivatives wherein R1-R12 are as defined in the specification act as antagonists of the P2X7 receptor. These compounds are particularly useful in the treatment of pain, inflammation and neurodegeneration states.
P2X7 antagonists for treating neuropathic pain
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Page/Page column 14, (2008/06/13)
The present invention discloses a method for treating neuropathic pain using compounds of formula I or compositions containing compounds of formula I.
