861401-17-4Relevant academic research and scientific papers
Effect of varying the 4″-position of arbekacin derivatives on antibacterial activity against MRSA and Pseudomonas aeruginosa
Hiraiwa, Yukiko,Minowa, Nobuto,Usui, Takayuki,Akiyama, Yoshihisa,Maebashi, Kazunori,Ikeda, Daishiro
, p. 6369 - 6372 (2007)
4″-Deoxy-4″-episubstituted arbekacin derivatives and 4″-epi-5-deoxy-5-episubstituted arbekacin derivatives were designed and synthesized. Arbekacin and 4″-epiarbekacin both displayed the same antibacterial activity against Staphylococcus aureus (including
NOVEL AMINOGLYCOSIDE ANTIBIOTIC EFFECTIVE AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (MRSA)
-
Page/Page column 70, (2010/11/24)
Disclosed are compounds represented by general formula (I) or pharmacologically acceptable salts or solvates thereof having excellent antimicrobial activity against bacteria causative of severe infections such as pneumonia and septicemia, particularly against MRSA, and also antimicrobial agents comprising these compounds, and pharmaceutical compositions comprising these compounds as an active component.
