86144-05-0Relevant academic research and scientific papers
Reactions with Radical Anions, II. Synthesis of 2-Aziridinecarbaldehyde Derivatives from Azomethines and gem-Dichloroalkanes and their 1H NMR Characterization
Dieck, Heindirk tom,Haupt, Erhard
, p. 1540 - 1546 (2007/10/02)
Radical anions from the alkali metal reduction of conjugated azomethines RN=CH-CH=NR (R=tert-butyl) react with alkyl halides R'X (R'=tert-butyl, ethyl) via relatively stable neutral radicals to give C-alkylated 6 or 8, resp., while dichloromethane or 1,1-dichloroethane form 2-aziridinecarbaldehyde imines 10-12.The complete 1H NMR analysis of all compounds is achieved, even for the mixture of diastereoisomers 11, 12, using the Double Indor Difference technique (DID) at 80 MHz.
