861445-20-7

Basic information

• Product Name: 5'-O-(4,4'-dimethoxytrityl)-2'-O-[1-(2-fluorophenyl)-4-methoxypiperidin-4-yl]-4-(1,2,4-triazolyl)uridine 3'-O-[2-cyanoethyl-N,N-(diisopropylamino)]phosphoramidite
• Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-[1-(2-fluorophenyl)-4-methoxypiperidin-4-yl]-4-(1,2,4-triazolyl)uridine 3'-O-[2-cyanoethyl-N,N-(diisopropylamino)]phosphoramidite
• CAS NO: 861445-20-7
• Molecular Weight: 1005.1
• Mol File: 861445-20-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5'-O-(4,4'-dimethoxytrityl)-2'-O-[1-(2-fluorophenyl)-4-methoxypiperidin-4-yl]-4-(1,2,4-triazolyl)uridine 3'-O-[2-cyanoethyl-N,N-(diisopropylamino)]phosphoramidite(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-(4,4'-dimethoxytrityl)-2'-O-[1-(2-fluorophenyl)-4-methoxypiperidin-4-yl]-4-(1,2,4-triazolyl)uridine 3'-O-[2-cyanoethyl-N,N-(diisopropylamino)]phosphoramidite(861445-20-7)
• EPA Substance Registry System: 5'-O-(4,4'-dimethoxytrityl)-2'-O-[1-(2-fluorophenyl)-4-methoxypiperidin-4-yl]-4-(1,2,4-triazolyl)uridine 3'-O-[2-cyanoethyl-N,N-(diisopropylamino)]phosphoramidite(861445-20-7)

Safety Data

• Hazardous Substances Data: 861445-20-7(Hazardous Substances Data)

Upstream product

• 288-88-0 1,2,4-Triazole 
• 131501-59-2 Diisopropyl-phosphoramidous acid (2R,3R,4R,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-[1-(2-fluoro-phenyl)-4-methoxy-piperidin-4-yloxy]-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester 

Relevant articles and documents

Synthesis of oligoribonucleotides containing 4-thiouridine using the convertible nucleoside approach and the 1-(2-fluorophenyl)-4-methoxypiperidin-4- yl group

Oligoribonucleotides containing 4-thiouridine were prepared using the Fpmp group for protection of the 2′-OH. Two uridine derivatives with the 1,2,4-triazolyl and the 2-nitrophenyl groups at position 4 were used to obtain 4-thiouridine by postsynthetic su